STEM CELL DONATION PROCESS
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Peripheral Blood Stem Cells Collection
For Stem Cell Donation, Firstly the donor should be the BEST MATCH for the patient which is identified by Human Leukocyte Antigen (HLA) Typing Test and secondly the donor needs to be MEDICALLY FIT to be able to donate.
STEPS in PBSC (Stem Cell) Donation:
- It is a non-surgical procedure performed in outpatient hospital facility, wherein donor’s blood is removed through a catheter (a thin, flexible plastic tube) and circulated into a blood cell separator machine called as Stem Cell Apheresis Device.
- This Apheresis Device filters out the STEM CELLS from the Donor's Blood & is transferred to a collection bag; the remaining Blood (plasma, red blood cells, and platelets) is injected back into the donor with another catheter.
- STEM CELLS COLLECTED are than preserved and infused into the patient after several hours for the Bone Marrow Transplant procedure to treat the patients.
- The PBSC (Stem Cell) donation is very SIMPLE procedure, wherein the Donor needs to be admitted in the Hospital only for 1 DAY ONLY wherein the procedure takes place for about 6-8 hours and needs to stay in India for 1 WEEK ONLY. Its a total RISK FREE and SAFE procedure.
- After donating Stem Cells, donor may experience some discomfort at the site where the needle was inserted, but this would gradually settle. A nurse will check on you regularly during donation and a physician will be onsite.
ANY QUESTIONS?
If you have any questions or queries you can CONTACT US anytime- Phone/ WhatsApp No.: +91-7015677759 Email ID: drvikas@bmtclinic.com.
Bone Marrow Harvesting
Bone marrow is one of the source of stem cells. Majority of children and patient undergoing Allogenic bone marrow transplant for benign hematological disorders get stem cell from donors bone marrow.
The harvesting procedure is done under general anesthesia in operating room. It involves little risk and minimal discomfort.
Bone marrow is collected from posterior superior iliac spine through harvesting needles. Usually two physician harvest bone marrow from both side, to reduce the collection time and anesthesia time. Several skin punctures on each hip and multiple bone punctures are usually required to extract the requisite amount of bone marrow. There are no surgical incisions or stitches involved – only skin punctures where the needle was inserted.
The amount of bone marrow harvested depends on the size of the patient and the concentration of bone marrow cells in the donor’s blood. Usually we collect 15 – 20 ml/kg (of donor’s weight) bone marrow. While this may sound like a lot, it really only represents about 2% of a person’s bone marrow, which the body replaces in four weeks.
When the effects of anesthesia disappear, donor may feel slight heaviness or pain at harvesting site, which usually get controlled with Acetaminophen (Paracetamol).
For autologous Transplant, the harvested bone marrow will be cryopreserved and stored at a temperature between -80 and -196 degrees centigrade until the day of transplant.
ANY QUESTIONS?
If you have any questions or queries you can CONTACT US anytime- Phone/ WhatsApp No.: +91-7015677759 Email ID: drvikas@bmtclinic.com.
